Views: 0 Author: Site Editor Publish Time: 2022-05-23 Origin: Site
Poria cocos sclerotia contains β- Poria cocos glycan accounts for about 93% of dry weight and triterpenoids acetylporia acid, Poria acid, 3 β- Hydroxylanosteroic acid. In addition, it also contains gum, chitin, protein, fat, sterol, lecithin, glucose, adenine, histidine, choline β- Poria cocos glycan decomposing enzyme, lipase, protease, etc.
Diuretic action
Poria cocos Decoction 3 g or the amount commonly used in clinic has no diuretic effect on healthy people. Intravenous injection of decoction 0.048 g / kg in dogs does not increase urine volume, nor does it have effect or very weak effect on rats. Oral Decoction in rabbits (close to the dosage of clinical people) does not increase urine volume. The extract of Poria cocos can promote the excretion of adrenal gland in rats or rabbits, but it can also be used in combination with water extract of Poria cocos, which is worthy of further study. Poria cocos contains 97.5 mg of potassium. Calculated by 30% decoction, it contains 0.186 mg / ml of sodium and 11.2 mg / ml of potassium. Therefore, the promotion of sodium excretion by Poria cocos has nothing to do with the content of sodium (because the content of sodium is too low), while the increase of potassium excretion is related to the large amount of potassium salt contained.
Wuling powder has obvious diuretic effect in dogs with chronic ureteral fistula (intravenous injection), healthy people and rabbits (oral Decoction) and rats. It can increase the excretion of sodium, potassium and chlorine in dogs, but the main diuretic drugs in Wuling powder are Cinnamon Twig, Alisma orientalis and Atractylodes macrocephala. It was also reported that Wuling powder decoction was orally administered to rats, and the dose increased to 1g / 100g also failed to prove its diuretic effect.
Antibacterial effect
No bacteriostatic effect of Poria cocos was found in the test tube. Alcohol extract can kill Leptospira, while water decoction is ineffective.
Effect on digestive system
Poria cocos has a direct relaxation effect on the isolated intestine of rabbits, has a preventive effect on the ulcer formed by pyloric ligation in rats, and can reduce gastric acid.
Other functions
Poria cocos can reduce blood sugar, tincture and extract can inhibit isolated toad heart, while ether or ethanol extract can strengthen cardiac contraction. It has no antiemetic effect on pigeon vomiting caused by digitalis.